Early Symptoms Of AIDS Mycobacterium avium complex

AIDS: Opportunistic Infections

Mycobacterium avium complex (MAC)

Mycobacterium avium complex (MAC), or mycobacterium avium intracellulare (MAI), is a bacterial infection that is caused by either Mycobacterium avium or Mycobacterium intracellulare. These bacteria are commonly found in water, soil, dust, and food.

In fact, these bacteria are present in almost every human. However, a healthy immune system prevents the bacteria from causing an infection. HIV/AIDS patients are at risk of developing MAC.

According to the CDC, MAC is considered an AIDS-defining illness. It is estimated that up to 50% of individuals with HIV/AIDS develop MAC, especially if their CD4 count is lower than 50 cells per microliter of blood. MAC rarely causes infections in patients who have CD4 cell counts higher than 100 cells per microliter of blood.

MAC infections may be localized (limited to one part of the body) or disseminated (spread throughout the entire body, sometimes called DMAC). MAC infection often occurs in the lungs, intestines, bone marrow, liver, and spleen.

abdominal pain, diarrhea, inflammation, and an overall feeling of weakness. MAC usually affects the intestines and inner organs first.

Common symptoms of MAC include:

  1. weight loss
  2. fever
  3. chills
  4. swollen glands
  5. abdominal pain
  6. diarrhea
  7. inflammation
  8. an overall feeling of weakness

The most common complication of DMAC is anemia (low levels of red blood cells), which may require a blood transfusion. If the infection involves many organs, it may lead to respiratory failure and death. Patients who have localized infections that have not spread to other parts of the body have a low mortality rate because they are easier to treat.