Herpes Licorice

Note
Alternative treatments/therapies should not replace your healthcare provider-led therapy/treatments. Patients should consult their healthcare providers before taking any herbs or supplements because they may interact with treatment.

Unclear or conflicting scientific evidence

Licorice

Licorice (Glycyrrhiza glabra) has been found in laboratory studies to hinder the spread and infection of the herpes simplex virus. Clinical studies need to be performed.

Avoid with a known allergy to licorice, any component of licorice, or any member of the Fabaceae (Leguminosae) plant family.

Avoid with congestive heart failure, coronary heart disease, kidney or liver disease, fluid retention, high blood pressure, hormonal abnormalities or if taking diuretics. Licorice can cause abnormally low testosterone levels in men or high prolactin or estrogen levels in women. This may make it difficult to become pregnant and may cause menstrual abnormalities.

Selected References
American Academy of Family Physicians. http://search.aafp.org. Accessed April 4, 2009.
American Social Health Association. www.ashastd.org. Accessed April 4, 2009.
Center for Disease Control and Prevention. www.cdc.gov. Accessed April 4, 2009.
Femiano F, Gombos F, Scully C. Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy. J Oral Pathol Med. 2005;34(7):423-5.
National Institute of Allergy and Infectious Diseases. www3.niaid.nih.gov. Accessed April 4, 2009.
Natural Standard: The Authority on Integrative Medicine. www.naturalstandard.com. Copyright © 2009. Accessed April 4, 2009.
Singh BB, Udani J, Vinjamury SP, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10(2):123-7.
Sun Y, Yang J. Experimental study of the effect of Astragalus membranaceus against herpes simplex virus type 1. Di Yi Jun Yi Da Xue Xue Bao. 2004;24(1):57-8.
Thomas SL, Wheeler JG, Hall AJ. Micronutrient intake and the risk of herpes zoster: a case-control study. Int J Epidemiol. 2006;35(2):307-14.
World Health Organization. www.who.int. Accessed April 4, 2009.
VZV Research Foundation. www.vzvfoundation.org. Accessed April 4, 2009.