Herpes Blessed thistle

Note
Alternative treatments/therapies should not replace your healthcare provider-led therapy/treatments. Patients should consult their healthcare providers before taking any herbs or supplements because they may interact with treatment.

Unclear or conflicting scientific evidence

Blessed thistle

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Laboratory studies report no activity of blessed thistle against herpes viruses, influenza, or poliovirus. Effects of blessed thistle (or chemicals in blessed thistle called lignans) against HIV are not clear. Human research of blessed thistle as a treatment for viral infections is lacking.

Blessed thistle is generally considered to be safe when taken by mouth in recommended doses for short periods of time, with few reported side effects such as birth defects, bleeding, breathing problems, bruising, cancer of the nose or throat, increased production of stomach acid, itching, kidney disease, liver toxicity, skin rash, stomach discomfort, stomach ulcers, and vomiting. Allergic reactions to blessed thistle including rash may occur, as well as cross-sensitivity to mugwort and Echinacea. Cross-reactivity may also occur with bitter weed, blanket flower, Chrysanthemum, coltsfoot, daisy, dandelion, dwarf sunflower, goldenrod, marigold, prairie sage, ragweed or other plants in the Asteraceae/Compositae family. Avoid if pregnant or breastfeeding.

Selected References
American Academy of Family Physicians. http://search.aafp.org. Accessed April 4, 2009.
American Social Health Association. www.ashastd.org. Accessed April 4, 2009.
Center for Disease Control and Prevention. www.cdc.gov. Accessed April 4, 2009.
Femiano F, Gombos F, Scully C. Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy. J Oral Pathol Med. 2005;34(7):423-5.
National Institute of Allergy and Infectious Diseases. www3.niaid.nih.gov. Accessed April 4, 2009.
Natural Standard: The Authority on Integrative Medicine. www.naturalstandard.com. Copyright © 2009. Accessed April 4, 2009.
Singh BB, Udani J, Vinjamury SP, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10(2):123-7.
Sun Y, Yang J. Experimental study of the effect of Astragalus membranaceus against herpes simplex virus type 1. Di Yi Jun Yi Da Xue Xue Bao. 2004;24(1):57-8.
Thomas SL, Wheeler JG, Hall AJ. Micronutrient intake and the risk of herpes zoster: a case-control study. Int J Epidemiol. 2006;35(2):307-14.
World Health Organization. www.who.int. Accessed April 4, 2009.
VZV Research Foundation. www.vzvfoundation.org. Accessed April 4, 2009.